SMOOTH SECOND ORDER SLIDING MODE CONTROL OF A CLASS OF UNDERACTUATED MECHANICAL SYSTEMS



Using bioinformatics approaches to identify survival-related oncomiRs as potential targets of miRNA-based treatments for lung adenocarcinoma

Lung cancer is a major cause of cancer-associated deaths worldwide, and lung adenocarcinoma (LUAD) is the most common lung cancer subtype.Micro RNAs (miRNAs) regulate the pattern of gene expression in multiple cancer types and have been explored as potential drug development targets.To develop an oncomiR-based panel, we identified miRNA candidates

read more

Future perspectives for PDE5 inhibitors bridging the gap between cardiovascular health and psychological status

Abstract The serendipitous discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of orally managing erectile dysfunction (ED) led to an increase in research data, which are currently considered groundbreaking for the new discip

read more